Right sided heart failure and pulmonary hypertension: New insights into disease mechanisms and treatment modalities
| Autor: | Juan C. Alejos, Ivan Wilmot, John L. Jefferies, Diana Drogalis-Kim |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pressure overload
medicine.medical_specialty business.industry Endothelin receptor antagonist Disease mechanisms Disease 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension 03 medical and health sciences 0302 clinical medicine Endocrinology 030228 respiratory system Progressive disorder Treatment modality Internal medicine Pediatrics Perinatology and Child Health Cardiology Medicine Cardiology and Cardiovascular Medicine business Right-sided heart failure |
| Zdroj: | Progress in Pediatric Cardiology. 43:71-80 |
| ISSN: | 1058-9813 |
| DOI: | 10.1016/j.ppedcard.2016.05.002 |
| Popis: | Pulmonary hypertension (PH), a rare chronic progressive disorder, is a well-established cause of right heart failure. Given that right heart function is the most important determinant of PH patient longevity Sandoval et al. (1994), D'Alonzo et al. (1991), Benza et al. (2010) [1–3], right heart pressure overload and failure secondary to PH is a critical aspect of the disease to review. In this article, we will highlight new research on the mechanisms of PH induced right heart failure, as well as review the latest PH treatments aimed at improving or sustaining right heart function. |
| Databáze: | OpenAIRE |
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