A combinatorial approach in designing hydrophilic surfaces for solid-phase peptide synthesis
| Autor: | Senake Perera, Francesca Ercole, Michael C. Fitzgerald, Rhonda Campbell, Phil Riley, Nicholas J. Ede |
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| Rok vydání: | 2003 |
| Předmět: |
chemistry.chemical_classification
Copolymer composition Materials science Polymers and Plastics Peptide General Chemistry Polyethylene Grafting Surfaces Coatings and Films chemistry.chemical_compound chemistry Chemical engineering Phase (matter) Polymer chemistry Materials Chemistry Peptide synthesis |
| Zdroj: | Journal of Applied Polymer Science. 89:3371-3378 |
| ISSN: | 1097-4628 0021-8995 |
| DOI: | 10.1002/app.12574 |
| Popis: | A hydrophilic surface suitable for solid-state peptide synthesis was developed on a solid support called a lantern. The split-and-mix combinatorial technique was used to prepare about 500 surfaces in a very short time. Surfaces were analyzed according to values for gel formation, percentage weight grafted, grafted copolymer composition, and number of functional groups per lantern. These values were correlated to the purity of a peptide synthesized on these surfaces. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 3371–3378, 2003 |
| Databáze: | OpenAIRE |
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