Doxapram and Potential Benzyl Alcohol Toxicity: A Moratorium on Clinical Investigation?

Autor:	GLENN D. JORDAN, NICHOLAS J. THEMELIS, SUSAN O. MESSERLY, ROBERT V. JARRETF, JOSE GARCIA, C. GILBERT FRANK
Rok vydání:	1986
Předmět:	Pediatrics Perinatology and Child Health
Zdroj:	Pediatrics. 78:540-541
ISSN:	1098-4275 0031-4005
DOI:	10.1542/peds.78.3.540
Popis:	To the Editor.— Barrington et al1 recently undertook an investigation designed to elucidate the mechanism of action and clinical effects of doxapram in neonates. There is currently considerable interest in the use of this agent as a therapeutic adjunct in cases of refractory apnea,2-4 and the study by Barrington et al offers important additional insights into the pharmacophysiology of this agent. However, as we reviewed the literature in preparation for using this agent at our institution, an alarming potential complication of doxapram usage emerged.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0e60da43e3cd05e33a44e69cf98747d6 https://doi.org/10.1542/peds.78.3.540 Zobrazit plný text záznamu