Changes of vitamins A and E in the rat retina under light and dark conditions detected with TOF-SIMS

Autor: Huaqing Gong, Miyako Tozu, Yoshiharu Ohashi, Kenichi Takaya, Tsugio Amemiya
Rok vydání: 2003
Předmět:
Zdroj: Applied Surface Science. :738-741
ISSN: 0169-4332
DOI: 10.1016/s0169-4332(02)00809-7
Popis: Vitamin A is a key material for visual function and its metabolism is always important topics in visual sciences. TOF-SIMS (SIMS: secondary ion mass spectrometry) can detect organic materials and elements in relation to the cell and tissue. Changes of vitamin A distribution in the rat retina under light and dark adaptations were detected with TOF-SIMS. Vitamin A is present in combination with polyunsaturated fatty acids in the living cell. Vitamin E participates in the membrane stability. Thus we examined not only vitamin A, but also vitamin E. In light condition, vitamins A and E were increased in the photoreceptor cell. These findings suggest that these vitamins are increased in the light exposed retina.
Databáze: OpenAIRE