Reaction of arylboronic acids with 5-aryl-3-substituted-2-thioxoimidazolin-4-ones

Autor: Dmitry A. Skvortsov, A. V. Finko, Yan A. Ivanenkov, Egor A. Dlin, Alexander G. Majouga, G.M. Averochkin, Nataliya S. Vorobyeva, Elena K. Beloglazkina, Nikolay V. Zyk, Victor Koteliansky
Rok vydání: 2016
Předmět:
Zdroj: Tetrahedron Letters. 57:5501-5504
ISSN: 0040-4039
Popis: A convenient and efficient catalytic procedure for the selective S-arylation of 2-thioxoimidazolidin-4-ones to give novel S-aryl substituted 2-thiohydantoins under mild reaction conditions using arylboronic acids is described. The anticancer activity of the compounds were evaluated in vitro.
Databáze: OpenAIRE