| Autor: |
Hiroshi Shiragami, Takashi Ineyama, Yumiko Uchida, Kunisuke Izawa, Satoshi Takamatsu, Yasuhiro Tanaka, Yoshihito Koguchi |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Nucleosides, Nucleotides and Nucleic Acids. 14:337-340 |
| ISSN: |
1525-7770 |
| DOI: |
10.1080/15257779508012376 |
| Popis: |
A convenient synthesis of 9-(2-hydroxyethoxymethyl)guanine (acyclovir) from guanosine by chemical transpurination was developed. The isomerization of the 7-isomer to the desired 9-isomer and the purification of the 9-isomer was achieved simply by concentration, heating and further crystallization. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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