Transcranial Magnetic Stimulation and Refractory Partial Epilepsy
| Autor: | Otto Trápaga Quincoses, Genco Marcio Estrada Vinajera, Lourdes Lorigados Pedre, Lilia María Morales Chacón, Lázaro Gómez Fernández, Luisa Rocha, Marilyn Zaldivar Bermudes |
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| Rok vydání: | 2013 |
| Předmět: |
Seizure frequency
medicine.diagnostic_test business.industry musculoskeletal neural and ocular physiology medicine.medical_treatment Stimulation Electroencephalography medicine.disease behavioral disciplines and activities Transcranial magnetic stimulation Clinical trial Epilepsy nervous system Refractory medicine business Neuroscience psychological phenomena and processes Partial epilepsy |
| Zdroj: | Pharmacoresistance in Epilepsy ISBN: 9781461464631 |
| Popis: | This chapter reviews the principles of transcranial magnetic stimulation (TMS) concerning its potential clinical use in diagnosis and therapy in medically intractable epilepsies. After introducing basic principles, stimulation protocols, and risks, TMS applications in epilepsies are summarized. Next, we discuss several clinical trials and animal studies, which show how low-frequency repetitive TMS (rTMS) may reduce seizure frequency and epileptiform discharges, mainly in focal epilepsy patients with neocortical epileptogenic zones such as malformations of cortical development. Lastly, we address some TMS effects on neurofunctional imaging. We conclude that rTMS should be considered one of the future noninvasive, relatively safe, and inexpensive therapeutic methods in patients with medically intractable epilepsies. |
| Databáze: | OpenAIRE |
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