Synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives from β-halo styrene derivatives and their application in the synthesis of trisubstituted pyridines
Autor: | Ching Fa Yao, Veerababurao Kavala, Trimurtulu Kotipalli, Ashok Konala, Chun Wei Kuo, Che Hao Hsu, Vijayalakshmi Bandi, Bharath Kumar Villuri |
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Rok vydání: | 2017 |
Předmět: | |
Zdroj: | RSC Adv.. 7:46704-46712 |
ISSN: | 2046-2069 |
Popis: | An approach for the synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives is reported starting from β-halo styrene and phenyl acetylene derivatives in the presence of PdCl2 and CuI catalysts. Functional groups such as aldehyde, cyano and ester groups are well tolerated and afford the desired functionalized dienynes. Further, these 1,3-buta-diene-3-yne derivatives are utilized for the synthesis of novel trisubstituted pyridine derivatives. |
Databáze: | OpenAIRE |
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