Synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives from β-halo styrene derivatives and their application in the synthesis of trisubstituted pyridines

Autor:	Ching Fa Yao, Veerababurao Kavala, Trimurtulu Kotipalli, Ashok Konala, Chun Wei Kuo, Che Hao Hsu, Vijayalakshmi Bandi, Bharath Kumar Villuri
Rok vydání:	2017
Předmět:	chemistry.chemical_classification 010405 organic chemistry General Chemical Engineering 1 3-Butadiene General Chemistry 010402 general chemistry 01 natural sciences Aldehyde 0104 chemical sciences Catalysis Styrene chemistry.chemical_compound chemistry Phenylacetylene Pyridine Organic chemistry
Zdroj:	RSC Adv.. 7:46704-46712
ISSN:	2046-2069
Popis:	An approach for the synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives is reported starting from β-halo styrene and phenyl acetylene derivatives in the presence of PdCl2 and CuI catalysts. Functional groups such as aldehyde, cyano and ester groups are well tolerated and afford the desired functionalized dienynes. Further, these 1,3-buta-diene-3-yne derivatives are utilized for the synthesis of novel trisubstituted pyridine derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0e4b929506264817169dfb6900871a86 https://doi.org/10.1039/c7ra07128k Zobrazit plný text záznamu