An Initial in Vitro Investigation into the Potential Therapeutic Use of Lucilia Sericata Maggot to Control Superficial Fungal Infections

Autor: Sulaiman Alnaimat, Milton Wainwright, Saleem Aladaileh
Rok vydání: 2013
Předmět:
Zdroj: Jordan Journal of Biological Sciences. 6:137-142
ISSN: 1995-6673
Popis: In this work an attempt was performed to investigate the in vitro ability of Lucilia sericata maggots to control fungi involved in superficial fungal infections. A novel GFP-modified yeast culture to enable direct visualization of the ingestion of yeast cells by maggot larvae as a method of control was used. The obtained results showed that the GFP-modified yeasts were successfully ingested by Lucilia sericata maggots and 1mg/ml of Lucilia sericata maggots excretions/ secretions (ES) showed a considerable anti-fungal activity against the growth of Trichophyton terrestre mycelium, the radial growth inhibition after 10 days of incubation reached 41.2 ±1.8 % in relation to the control, these results could lead to the possible application of maggot therapy in the treatment of wounds undergoing fungal infection.
Databáze: OpenAIRE