Évaluation d’un test rapide immuno-chromatographique comme aide à la prophylaxie antitétanique dans un service d’urgences

Autor:	Paul Gérard, Jean Duchateau, Jean Christophe Cavenaile
Rok vydání:	2012
Předmět:	Gynecology medicine.medical_specialty Immune status Tetanus business.industry Biochemistry (medical) Clinical Biochemistry Gold standard (test) Emergency department medicine.disease Surgery Clinical history medicine Elisa method business
Zdroj:	Immuno-analyse & Biologie Spécialisée. 27:185-190
ISSN:	0923-2532
Popis:	Summary Introduction Preventing tetanus performed in emergency department is not optimal when based on history. In 2005 appeared an immunochromatographic rapid test (TQS), which allows a semiquantitative determination of tetanus antibodies. Objectives To perform a validity study of the test and to compare its performance with the performance of clinical history. Methods In a prospective double-blind study, we have tested the accuracy of the test and compared its performance with the performance of clinical history. The measure of the antibodies by ELISA method was the gold standard. Results The sensitivity and specificity of TQS were respectively 93% and 94%, while the sensitivity and specificity of the clinical history were respectively 41% and 85%. Conclusions The TQS was considered well above the history to determine the immune status of patients. Its use in the prevention of tetanus is possible in emergency departments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0e21a6a2fa39da7c6afc3ba54a1d7f6d https://doi.org/10.1016/j.immbio.2012.01.011 Zobrazit plný text záznamu Full Text from ScienceDirect