Abstract 13333: Systolic Blood Pressure Is An Independent Risk Factor For Diabetic Retinopathy In Both Hypertensive And Normotensive Patients

Autor: Yu-Ting Li, Yi Wang, Xiu-Jing Hu, Bedru H. Mohammed, Xiao-Ling Liang, Jose Hernandez, Wen-Yong Huang, Harry H.X. Wang
Rok vydání: 2021
Předmět:
Zdroj: Circulation. 144
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circ.144.suppl_1.13333
Popis: Introduction: Treatments with targets of systolic blood pressure (BP) Hypothesis: We assessed the hypothesis that systolic BP levels were not associated with DR in normotensive patients. Methods: This was a baseline analysis of a cohort of adult Chinese patients diagnosed with type 2 diabetes who attended ophthalmoscopic exam with primary care referral in the context of a Specialist-Generalist Working Alliance in Guangzhou, China. A hospital-based, standardised investigation included a dilated, comprehensive eye examination, a measurement of BP values and anthropometric parameters, and a clinical laboratory test for haemoglobin A1c and lipid profiles. A binary logistic regression analysis was conducted to examine patient-level risk factors associated with DR. Results: The mean age of all study participants (N=2,510) was 64.8 years, and more than half were females. More than one in three patients (40.4%) were normotensive. The average duration of diabetes was 8.6 years, and one in five patients were clinically diagnosed with DR. A higher systolic BP level was significantly associated with DR (adjusted odds ratio [aOR]=1.019, 95%CI: 1.012-1.027; p Conclusions: In conclusion, we found that increased systolic BP level was an independent, significant risk factor associated with DR in both hypertensive and normotensive diabetic patients. Physicians, patients and caregivers are recommended to maintain regular monitoring of BP in all diabetic patients irrespective of the coexistence of hypertension.
Databáze: OpenAIRE