Microalgae as natural sources for antioxidative compounds

Autor: Rainer Buchholz, Christian Walter, Barbara C. Klein, Harald A. Lange
Rok vydání: 2011
Předmět:
Zdroj: Journal of Applied Phycology. 24:1133-1139
ISSN: 1573-5176
0921-8971
DOI: 10.1007/s10811-011-9743-7
Popis: Antioxidants are substances that have the ability to reduce free, energized radicals. Thus, they prevent the oxidation of sensitive metabolites like lipids or amino acids and shield them from being destroyed by interrupting auto- or photooxidative chain reactions inside the cell. Antioxidants are also of industrial importance because they can be used as food, drug, or plastics additives. Ubiquinol, the reduced form of coenzyme Q10, is one of the most effective antioxidants in human cells. This paper explores optimization strategies to increase Q10 concentration in the biomass of Porphyridium purpureum, based on the variation of photosynthetic photon flux density. In addition, a cultivation process was performed in the 120-L scale followed by an automized extraction procedure (Accelerated Solvent Extraction®) resulting in an increase of the product recovery by a factor of 14 compared to the standard extraction method, hence reaching a specific coenzyme Q10 concentration of 141 μg gdry weight−1 and a volumetric coenzyme Q10 concentration of 1.96 mg L−1, respectively.
Databáze: OpenAIRE
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