The Comparative Study of Parathyroid Hormone with Bone Histomorphometry in Long-term Hemodialysis Patients

Autor: Jirou Ogata, Shogo Masumi, Hirokazu Yano, Shinichi Kawano, Tohru Fujiwara, Kazuhiro Takagi, Katsuhiko Terada, Yoshio Nomura
Rok vydání: 1991
Předmět:
Zdroj: Orthopedics & Traumatology. 39:1331-1334
ISSN: 1349-4333
0037-1033
DOI: 10.5035/nishiseisai.39.1331
Popis: Bone biopsies were studied in 10 long-term hemodialysis patients to determine if a serum comcentration of intact-PTH is a better predictor of ostitis fibrosa than that of carboxyterminal PTH fragment.A serum concentration of intact-PTH correlated positively with fibrous tissue specific volume and serum alkaline phosphatase level. Moreover, intact-PTH reflected more clearly subperiosteal resorption in radiological findings than c-PTH. These data suggest that a serum concentration of intact-PTH may be a better predictor of ostitis fibrosa than that of c-PTH.
Databáze: OpenAIRE