Practical synthetic routes to carbon-substituted nucleosides

Autor: David Leese, Donald Stuart Middleton, James Hart, Rebecca Glen, Xiurong Zhang, David C. Pryde, P. G. Wainwright, Neil Forrest, Thierry Guyot, Adrian Maddaford, Peter T. Stephenson
Rok vydání: 2011
Předmět:
Zdroj: Tetrahedron Letters. 52:6415-6419
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2011.09.074
Popis: Robust practical routes to three different carbon-substituted nucleosides are described. Short synthetic procedures for preparing 1′-homonucleosides, 2′- C -methyl-carbanucleosides and 2′- C -methyl-cyclopropyl/cyclopentyl fused bicyclic ribose analogues are described starting from readily available building blocks.
Databáze: OpenAIRE