Human Immunodeficiency Virus Type 1 RNA Levels in Rectal and Seminal Compartments After Switching to Long-Acting Cabotegravir Plus Rilpivirine: A Longitudinal Study

Autor: Mar Masiá, Marta Fernández-González, Vanesa Agulló, Paula Mascarell, Sergio Padilla, Javier García-Abellán, Félix Gutiérrez
Rok vydání: 2022
Předmět:
Zdroj: Clinical Infectious Diseases. 76:e748-e751
ISSN: 1537-6591
1058-4838
DOI: 10.1093/cid/ciac676
Popis: Human immunodeficiency virus type 1 RNA levels were longitudinally evaluated in 211 rectal and 152 seminal samples from 12 virologically suppressed participants switching to monthly long-acting cabotegravir plus rilpivirine or continuing with daily dolutegravir-abacavir-lamivudine. Maintenance of viral suppression in rectal and seminal compartments was comparable, and blips occurred with similar frequency with both treatment regimens. Clinical Trials Registration NCT02938520.
Databáze: OpenAIRE