Human Immunodeficiency Virus Type 1 RNA Levels in Rectal and Seminal Compartments After Switching to Long-Acting Cabotegravir Plus Rilpivirine: A Longitudinal Study
Autor: | Mar Masiá, Marta Fernández-González, Vanesa Agulló, Paula Mascarell, Sergio Padilla, Javier García-Abellán, Félix Gutiérrez |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Clinical Infectious Diseases. 76:e748-e751 |
ISSN: | 1537-6591 1058-4838 |
DOI: | 10.1093/cid/ciac676 |
Popis: | Human immunodeficiency virus type 1 RNA levels were longitudinally evaluated in 211 rectal and 152 seminal samples from 12 virologically suppressed participants switching to monthly long-acting cabotegravir plus rilpivirine or continuing with daily dolutegravir-abacavir-lamivudine. Maintenance of viral suppression in rectal and seminal compartments was comparable, and blips occurred with similar frequency with both treatment regimens. Clinical Trials Registration NCT02938520. |
Databáze: | OpenAIRE |
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