015 Long-term (1-year) seizure freedom with adjunctive perampanel in paediatric patients with epilepsy: study 311

Autor:	Robert Flamini, Anna Patten, Manoj Malhotra, Leock Y Ngo
Rok vydání:	2022
Předmět:	Psychiatry and Mental health Surgery Neurology (clinical)
Zdroj:	Journal of Neurology, Neurosurgery & Psychiatry. 93:A105.3-A105
ISSN:	1468-330X 0022-3050
DOI:	10.1136/jnnp-2022-abn.340
Popis:	BackgroundLong-term (1-year) seizure-freedom rates with adjunctive perampanel were assessed in paediatric patients aged 4–NCT02849626).MethodsSeizure-freedom rates (FOS, FBTCS, GTCS) were assessed in patients who achieved seizure freedom during the Core Study Maintenance Period and then remained seizure free for up to 12 months (calculated from the start of their seizure-free period). Data were stratified by concomitant enzyme- inducing anti-seizure medications (EIASMs) (with and without) and age (4–ResultsFor FOS, 6/11 (54.5%) patients remained seizure free for 12 months (with EIASMs, n=2/5 [40.0%]; without EIASMs, n=4/6 [66.7%]; 4–ConclusionDespite small patient numbers, seizure-freedom rates are maintained during long-term (1-year) perampanel treatment in paediatric patients, consistent with analyses in adolescents/adults.Funding.Eisai Inc. stella_ngo@eisai.com
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0deb1e98c9e09e10a177d49128614fd5 https://doi.org/10.1136/jnnp-2022-abn.340 Zobrazit plný text záznamu