Multiple ileal ulcers and an ileal Dieulafoy's lesion induced by loxoprofen sodium
| Autor: | Mototsugu Kato, Tomotaka Takagi, Yasuyuki Kunieda, Masahiro Asaka, Masato Nakayama, Shigeto Yoneyama, Masae Ooishi, Suzuki G, Tadahumi Ishizaki, Takashi Kato, Nobuhisa Nakajima |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Sodium chemistry.chemical_element Scintigraphy digestive system Gastroenterology Lesion Ileal Ulcer Internal medicine Medicine Radiology Nuclear Medicine and imaging Adverse effect medicine.diagnostic_test business.industry digestive oral and skin physiology Loxoprofen Dieulafoy's lesion medicine.disease digestive system diseases Surgery chemistry medicine.symptom business Wedge resection (lung) medicine.drug |
| Zdroj: | Digestive Endoscopy. 15:243-246 |
| ISSN: | 1443-1661 0915-5635 |
| DOI: | 10.1046/j.1443-1661.2003.00255.x |
| Popis: | Loxoprofen sodium is one of the non-steroidal anti-inflammatory drugs (NSAIDs) that is a prodrug. Several adverse effects of the drug have been described, but ileal ulcer has not been reported so far. We experienced an 87-year-old male patient with disk herniation complicated with loxoprofen sodium-induced multiple ileal ulcers and an ileal Dieulafoy's lesion that caused massive intestinal bleeding. The patient was saved by wedge resection of the Dieulafoy's lesion and discontinuance of the NSAID. 99mTc-red blood cell scintigraphy and intraoperative enteroscopy of the small bowel were useful in the diagnosis. This is the first case of multiple ileal ulcers with an ileal Dieulafoy's lesion induced by loxoprofen sodium. |
| Databáze: | OpenAIRE |
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