Experimental salicylate intoxication in young baboons

Autor:	C. Eyberg, H. Kundig, N. Buchanan
Rok vydání:	1975
Předmět:	Pathogenesis medicine.medical_specialty Endocrinology Biochemistry Salicylate intoxication business.industry Internal medicine Pediatrics Perinatology and Child Health Medicine Serum concentration medicine.symptom business Acidosis
Zdroj:	The Journal of Pediatrics. 86:225-232
ISSN:	0022-3476
Popis:	Salicylate intoxication has been investigated in young baboons. The results of these studies are similar to these previously obtained in man. Acidosis appears to be of considerable importance in the pathogenesis of infantile salicylism as it enhances the passage of salicylate into the CSF. The CSF concentration of salicylate seems to be of major physiologic importance in this condition. Moreover, the serum concentration of free salicylate correlates more closely with the CSF concentration of salicylate than does the total serum concentration of salicylate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0dc9bcb4e539c54b6ca6a7b4c0f3bb11 https://doi.org/10.1016/s0022-3476(75)80473-2 Zobrazit plný text záznamu