| Autor: | Klaus Lederer, Michael Parth, Nicolai Aust |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Ultra-high-molecular-weight polyethylene
Materials science Radical Size-exclusion chromatography technology industry and agriculture Biomedical Engineering Biophysics Bioengineering Polyethylene Scavenger Biomaterials chemistry.chemical_compound chemistry Polymer chemistry Molar mass distribution Tocopherol Irradiation Nuclear chemistry |
| Zdroj: | Journal of Materials Science: Materials in Medicine. 13:917-921 |
| ISSN: | 0957-4530 |
| DOI: | 10.1023/a:1019892004830 |
| Popis: | Ultra-high molecular weight polyethylene (UHMW-PE) is being used successfully for articulating surfaces in joint endoprostheses, especially for cups of total hip endoprostheses. Sintered specimens containing various amounts of α-tocopherol (vitamin E) as a biocompatible stabilizer, were irradiated in nitrogen atmosphere as well as in air with various dosages of electron beam radiation. Size exclusion chromatography (SEC) was used to analyze the soluble fractions of the UHMW-PE samples according to their molecular weight distribution prior to and after irradiation. In nitrogen atmosphere the radiation-induced crosslinking showed to be dependent on the added amount of α-tocopherol in the sintered specimens. With an increasing content of α-tocopherol, the stabilizer acted as a scavenger for free radicals. Thus, the crosslinking was more and more hindered. The same effect was observed on the samples irradiated in air, where, in addition to the crosslinking process, oxidative molecular degradation occurred. The highest extent of crosslinked material was yielded with unstabilized samples in nitrogen atmosphere. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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