Experimental elimination of confronting cisternae in HeLa cells

Autor:	J. R. Palisano
Rok vydání:	1991
Předmět:	HeLa biology General Medicine biology.organism_classification Cell biology
Zdroj:	Proceedings, annual meeting, Electron Microscopy Society of America. 49:244-245
ISSN:	2690-1315 0424-8201
DOI:	10.1017/s0424820100085526
Popis:	Although confronting cisternae (CC) were described in 1955, very little is known about their origin or function. CC have been observed in a variety of tumor cells and normal fetal rat, mouse, and human epithelial tissues. While some evidence suggests that CC arise from the nuclear envelope (NE) folding back on itself during prophase, the question remains why are CC not seen in all mitotic cells or in all tumor cells instead of selected tumor cells. These seemingly inconsistent observations have led investigators to suggest that the occurrence of CC is a phenomenon resulting from the cells rapid progress through mitosis. This hypothesis was tested during HeLa cell synchronization studies which enabled the investigator to control the movement of the cells through mitosis.
Databáze:	OpenAIRE
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