Relationship between hypothyroidism and carotid artery intima media thickness, and prevalence of hypothyroidism in rheumatoid arthritis patient: An observational study
| Autor: | A Dey, Tanmoy W Momin, Somnath Dasgupta, Mrinal Kanti Ghosh, Kishore Shaw, Jayanta Paul |
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| Rok vydání: | 2012 |
| Předmět: |
endocrine system
medicine.medical_specialty education.field_of_study endocrine system diseases business.industry Carotid arteries Population medicine.disease Endocrinology Intima-media thickness Internal medicine Rheumatoid arthritis medicine Observational study Statistical analysis Risk factor business education hormones hormone substitutes and hormone antagonists |
| Zdroj: | Thyroid Research and Practice. 9:45 |
| ISSN: | 0973-0354 |
| DOI: | 10.4103/0973-0354.96035 |
| Popis: | Introduction: Rheumatoid arthritis (RA) and hypothyroidism both are associated with atherosclerosis. Prevalence of hypothyroidism is higher in RA than in general population. But there is still controversy regarding relationship between carotid artery intima media thickness (CAIMT) and hypothyroidism. Aims and Objectives: This study was done to find out prevalence of hypothyroidism in RA and relationship between hypothyroidism and CAIMT in RA patients. Materials and Methods: The study subjects included 52 RA patients. Among them, 8 RA patients were suffering from hypothyroidism. CAIMT was measured by B-mode ultrasound. Statistical analysis was performed by SPSS software (17 th edition for window). Result and Analysis: 15.4% of RA patients were suffering from hypothyroidism. There was also independent correlation between CAIMT and hypothyroidism in RA (P = 0.044). CAIMT of RA with hypothyroidism was significantly higher than RA without hypothyroidism (P = 0.023). Conclusion: Prevalence of hypothyroidism is higher in RA than in general population. Hypothyroidism is an independent risk factor of atherosclerosis in RA patients. |
| Databáze: | OpenAIRE |
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