Solitary spinal nephroblastoma progressing to multifocal disease in a dog
| Autor: | David Lurie, Sonya Yu, David Taylor, Karon Hoffmann |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Nervous system
medicine.medical_specialty Pathology General Veterinary medicine.diagnostic_test 040301 veterinary sciences business.industry medicine.medical_treatment Magnetic resonance imaging 04 agricultural and veterinary sciences medicine.disease Spinal cord Metastasis 0403 veterinary science Radiation therapy Lesion 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure medicine Histopathology medicine.symptom business 030217 neurology & neurosurgery Paresis |
| Zdroj: | Veterinary Record Case Reports. 6 |
| ISSN: | 2052-6121 |
| DOI: | 10.1136/vetreccr-2018-000665 |
| Popis: | A two- year-old neutered Labrador dog was evaluated for acute onset hindlimb paresis and proprioceptive deficits. Spinal MRI revealed a lesion at the level of T9–T10, from which a presumptive diagnosis of spinal nephroblastoma was made. The dog showed clinical improvement after receiving neoadjuvant stereotactic radiotherapy but re-presented six weeks later with neurological deterioration. In addition to the primary lesion, a repeat MRI study revealed lesions at T6–T7 and T12. The dog was euthanased and multiple intradural, extramedullary spinal cord lesions were found at postmortem examination. Histopathological analysis of the lesions confirmed spinal nephroblastoma. This report substantiates the likelihood of intraspinal metastases of nephroblastoma occurring in the dog. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text