Wntrepertoire and developmental expression patterns in the crustaceanThamnocephalus platyurus
| Autor: | Terri A. Williams, A. J. Stangl, Ryan M. Pace, Lisa M. Nagy, Savvas J. Constantinou |
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| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
0301 basic medicine Cloning Regulation of gene expression animal structures Sequence analysis fungi Wnt signaling pathway Anatomy Biology 010603 evolutionary biology 01 natural sciences 03 medical and health sciences 030104 developmental biology Phylogenetics Evolutionary biology Subfunctionalization Gene family Axis elongation Ecology Evolution Behavior and Systematics Developmental Biology |
| Zdroj: | Evolution & Development. 18:324-341 |
| ISSN: | 1520-541X |
| DOI: | 10.1111/ede.12204 |
| Popis: | Wnt genes are a family of conserved glycoprotein ligands that play a role in a wide variety of cell and developmental processes, from cell proliferation to axis elongation. There are 13 Wnt subfamilies found among metazoans. Eleven of these appear conserved in arthropods with a pattern of loss during evolution of as many as six subfamilies among hexapods. Here we report on Wnt genes in the branchiopod crustacean, Thamnocephalus platyurus, including the first documentation of the expression of the complete Wnt gene family in a crustacean. Our results suggest fewer Wnt genes were retained in Thamnocephalus than in the related crustacean, Daphnia, although the Thamnocephalus Wnt repertoire is larger than that found in insects. We also find an intriguing pattern of staggered expression of Wnts-an anterior-posterior stagger within the posterior growth zone and a dorsal-ventral stagger in the developing segments-suggesting a potential for subfunctionalization of Wnts in these regions. |
| Databáze: | OpenAIRE |
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