Device-related Mycobacterium mageritense Infection in a Patient Treated with Nivolumab for Metastatic Breast Cancer

Autor: Hironobu Minami, Yoshimi Fujishima, Sho Nishimura, Masanori Toyoda, Naomi Kiyota, Taiji Koyama, Yoshinori Imamura, Yohei Funakoshi, Hirokazu Tanino
Rok vydání: 2021
Předmět:
Zdroj: Internal Medicine. 60:3485-3488
ISSN: 1349-7235
0918-2918
Popis: Treatment with anti-programmed cell death-1 (PD-1) antibodies improves the anti-cancer immune response and can provide a meaningful clinical benefit to cancer patients. However, this treatment can result in specific autoimmune toxicities, termed immune-related adverse events (irAEs). Although irAEs are well recognized, the development of infectious diseases due to this treatment is not often observed. Some recent reports have indicated that patients who receive anti-PD-1 antibodies are at a higher risk for tuberculosis than others. However, reports on nontuberculous mycobacterial infection during anti-PD-1 antibody treatment are still rare. We herein report the first case of Mycobacterium mageritense infection during anti-PD-1 antibody treatment.
Databáze: OpenAIRE