The Effects of Lifetime Food Restriction on the Development of Osteoarthritis in the Canine Shoulder

Autor:	Dennis F. Lawler, Jeffrey J. Runge, Richard D. Kealy, Thomas P. Gregor, Richard H. Evans, Gail K. Smith, Stephanie D. Szabo, Darryl N. Biery
Rok vydání:	2008
Předmět:	medicine.medical_specialty General Veterinary Shoulders business.industry Osteoarthritis medicine.disease Surgery medicine.anatomical_structure Quality of life Internal medicine Severity of illness medicine Shoulder joint Histopathology Clinical significance business Cohort study
Zdroj:	Veterinary Surgery. 37:102-107
ISSN:	0161-3499
Popis:	Objective— To report effects of age and lifetime food restriction on development and progression of shoulder joint osteoarthritis (OA) in Labrador retriever dogs. Study Design— Longitudinal life-span, cohort study. Animals— Labrador retriever dogs (n=48). Methods— Littermates were paired (gender, weight) to make 24 pairs of genetically similar dogs. Each diet-restricted (DR) pair-mate was fed daily 75% of the same diet consumed by its control-fed (CF) pair-mate for life. Shoulders were evaluated radiographically at years 6, 8, and end of life (EOL). At EOL shoulders were evaluated grossly and by histopathology for OA. Results— Radiographic evidence of shoulder OA was identified in 78% of dogs. Severity of radiographic shoulder OA at 6 (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0d9eeb20653376e812eb319cf046ae74 https://doi.org/10.1111/j.1532-950x.2007.00354.x Zobrazit plný text záznamu Plný text