| Popis: |
Biochips constitute a rapidly increasing research field driven by the versatility of sensing devices and the importance of their applications in the bioanalytical field, drug development, environmental monitoring, food analysis, etc. Common strategies used for creating biochips and for reading them have extensive limitations, motivating development of miniature biochips and label‐free formats.To achieve these goals we combined the nano fountain pen method, for printing microscale features with Raman spectroscopy or surface enhanced Raman spectroscopy (SERS) for reading droplets of synthetic receptors. These receptors include molecularly imprinted polymers (MIPs), which are obtained by polymerization of suitable functional and cross‐linking monomers around molecular templates. MIPs are characterized by higher physical and chemical stability than biomacromolecules, and therefore are potentially very suitable as recognition elements for biosensors, or biochips.The monitored bands in the Raman and SERS spectr... |
