Autor:	M Koulentaki, Elias A. Kouroumalis, H. Oekonomaki, Maria Tzardi, Efthimia Petinaki, Ioannis E. Koutroubakis, Ioannis A. Mouzas
Rok vydání:	1999
Předmět:	Autoimmune disease medicine.medical_specialty education.field_of_study Physiology business.industry Biliary cirrhosis Population Gastroenterology Hepatology medicine.disease Inflammatory bowel disease Ulcerative colitis Primary biliary cirrhosis Internal medicine medicine Colitis business education
Zdroj:	Digestive Diseases and Sciences. 44:1953-1956
ISSN:	0163-2116
DOI:	10.1023/a:1026697613173
Popis:	Primary biliary cirrhosis and ulcerative colitis are two diseases with many features of autoimmunity. Thirteen cases of coexistence of the two diseases have been reported in the literature so far. Patients are usually younger and more often males than the ordinary primary biliary cirrhosis patient, while the colitis is mild and easily controllable. In a homogeneous population of 550,000 inhabitants of the island of Crete, 412 cases of ulcerative colitis and 82 individuals with primary biliary cirrhosis or autoimmune cholangitis have been identified. In two cases, coexistence of the two diseases was found. Immunological screening for AMA positivity in 150 ulcerative colitis sera disclosed no further cases. Prevalence of primary biliary cirrhosis in ulcerative colitis patients seems at least 30 times higher than in the general population in our area. A possible immunological link between the two diseases is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0d696bd6b9ab8cc9d287bdf43b7d2b97 https://doi.org/10.1023/a:1026697613173 Zobrazit plný text záznamu Full text from SpringerLink