ROLE OF UNDIFFERENTIATED DYSPLASIA OF THE CONNECTIVE TISSUE IN THE DEVELOPMENT OF SPINE PATHOLOGY COMBINED WITH JUVENILE GLAUCOMA AND MYOPIA
| Rok vydání: | 2008 |
|---|---|
| Předmět: |
Pathology
medicine.medical_specialty genetic structures business.industry medicine.disease eye diseases Sclera Anesthesiology and Pain Medicine Atrophy medicine.anatomical_structure Ophthalmologic examination Cardiac valve Connective tissue dysplasia Medicine Orthopedics and Sports Medicine Surgery In patient sense organs business Optical topography Primary juvenile glaucoma |
| Zdroj: | Hirurgiâ pozvonočnika. :80-85 |
| ISSN: | 1810-8997 |
| DOI: | 10.14531/ss2008.1.80-85 |
| Popis: | Objective. To study the influence of connective tissue dysplasia on the development of spine pathology, cardiovascular system, primary juvenile glaucoma, and myopia basing on a multimodal orthopaedic, pathomorphological, and ophthalmological examination for optimization of diagnosis and treatment. Material and Methods. The multimodal examination of 50 patients with spine pathology combined with a primary juvenile glaucoma and acquired progressing myopia was performed. All patients passed through ophthalmologic, clinical-genealogical, orthopaedic, and cardiologic examination, with biochemical and pathomorphological investigation of surgical specimens. Spine pathology was assessed by a computer optical topography method. Results. Connective tissue dysplasia in patients with spine pathology is associated with ophthalmopathology and anomalies of cardiac valve and notochord. Structural metabolic changes of connective-tissue components of juxtacanalicular zone and sclera cause degenerative-dystrophic process accompanied by a dysfunction of eye drainage system synchronized with optic atrophy. Conclusion. Patients with spine pathology, with outer and innate phenotypic signs of connective tissue dysplasia should be referred to diagnostic ophthalmologic examination for detection and early treatment of acquired myopia and primary juvenile glaucoma. |
| Databáze: | OpenAIRE |
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