Identification of predictive markers of response in colorectal cancer following treatment with dasatinib, an orally active tyrosine kinase inhibitor of ABL and SRC

Autor: Judy Dering, Amrita Desai, Ondrej Kalous, DJ Slamon, Richard S. Finn, J. R. Hecht, E. Clark, Zev A. Wainberg, Charles Ginther, Adrian Anghel
Rok vydání: 2008
Předmět:
Zdroj: Journal of Clinical Oncology. 26:14688-14688
ISSN: 1527-7755
0732-183X
Popis: 14688 Background: Elevated levels of Src kinase have been implicated in the malignant potential of colorectal cancer. Dasatinib is an orally active, multi-targeted tyrosine kinase inhibitor of ABL ...
Databáze: OpenAIRE