Synthesis of 2,4-dimethylglutaric acid monoesters via enzyme-catalyzed asymmetric alcoholysis of meso-2,4-dimethylglutaric anhydride
| Autor: | Rüdiger Ozegowski, Hans Schick, Annamarie Kunath |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
chemistry.chemical_classification
biology Organic Chemistry Enantioselective synthesis Triacylglycerol lipase Catalysis Inorganic Chemistry Dicarboxylic acid chemistry Yield (chemistry) biology.protein Organic chemistry Physical and Theoretical Chemistry Lipase Enantiomeric excess Aliphatic compound |
| Zdroj: | Tetrahedron: Asymmetry. 4:695-698 |
| ISSN: | 0957-4166 |
| Popis: | 1-(2-Methylpropyl) 5-hydrogen (2 R ,4 S )-2,4-dimethylpentanedioate with an enantiomeric excess of 90 % was obtained in a yield of 72 % from meso -2,4-dimethylpentanedioic anhydride and 2-methylpropanol by an asymmetric alcoholysis catalyzed by the lipase from Candida sp. 382 . |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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