Development, Progression, and Regression of Microalbuminuria in Japanese Patients With Type 2 Diabetes Under Tight Glycemic and Blood Pressure Control

Autor: Yukino Shima, Toru Aizawa, Mitsuko Matsuzaki, Yuka Ishikawa, Mika Fujiwara, Nobuko Furusato, Reiko Mita, Yasuhiro Miyahara, Mitsuhisa Komatsu, Kazue Nishi, Ichiro Komiya, Takashi Yamada
Rok vydání: 2005
Předmět:
Zdroj: Diabetes Care. 28:2733-2738
ISSN: 1935-5548
0149-5992
DOI: 10.2337/diacare.28.11.2733
Popis: OBJECTIVE— The goal of this study was to know the fate of albuminuria in Japanese patients with type 2 diabetes under tight blood pressure and glycemic control. RESEARCH DESIGN AND METHODS— Patients having normoalbuminuria (urinary albumin excretion RESULTS— Development occurred in 27 (15%) of the normoalbuminuric patients and progression and regression in 16 (17%) and 20 (21%), respectively, of the microalbuminuric patients. Significant independent relationships existed between development and higher achieved mean systolic blood pressure (SBP) and regression and lower achieved mean SBP. In the patients with achieved mean SBP CONCLUSIONS— Development and progression were low and regression was high with SBP of 120 mmHg, provided A1C was maintained at 6.5%.
Databáze: OpenAIRE