Mitochondrial DNA polymorphisms in Chilean aboriginal populations: Implications for the peopling of the southern cone of the continent

Autor: Flavio Nervi, Juan Francisco Miquel, Pilar Carvallo, Elena Llop, Francisco Rothhammer, Paola Rocco, Ranajit Chakraborty, Mauricio Moraga
Rok vydání: 2000
Předmět:
Zdroj: American Journal of Physical Anthropology. 113:19-29
ISSN: 1096-8644
0002-9483
DOI: 10.1002/1096-8644(200009)113:1<19::aid-ajpa3>3.0.co;2-x
Popis: The mitochondrial DNAs (mtDNAs) from individuals be- longing to three Chilean tribes, the Mapuche, the Pehuenche, and the Yaghan, were studied both by RFLP analysis and D-loop (control region) sequencing. RFLP analysis showed that 3 individuals (1.3%) belonged to haplogroup A, 19 (8%) to haplogroup B, 102 (43%) to haplogroup C, and 113 (47.7%) to haplogroup D. Among the 73 individuals analyzed by D-loop sequencing, we observed 37 different haplotypes defined by 52 polymorphic sites. Joint analysis of data obtained by RFLP and sequencing methods demonstrated that, regardless of the method of analysis, the mtDNA haplo- types of these three contemporary South American aborigine groups clus- tered into four main haplogroups, in a way similar to those previously described for other Amerindians. These results further revealed the absence of haplogroup A in both the Mapuche and Yaghan as well as the absence of haplogroup B in the Yaghan. These results suggest that the people of Tierra del Fuego are related to tribes from south-central South America. Am J Phys Anthropol 113:19 -29, 2000. © 2000 Wiley-Liss, Inc. The analysis of mitochondrial DNA vari- ation has been extensively used in the re- cent past, for genetic characterization of contemporary aboriginal populations of the Americas. The primary goals of this analy- sis have been to determine the origins, re- lationships, and migrational patterns of New World populations. In this respect, the study of the frequency distribution of the four founding Amerindian haplogroups, suggested by Schurr et al. (1990) and de- fined by Torroni et al. (1992), has proven useful.
Databáze: OpenAIRE
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