Production and Applications of Spin-Polarized Isotopes of Noble Gases

Autor: Sh. Sh. Nabiev, G. Yu. Grigor’ev
Rok vydání: 2018
Předmět:
Zdroj: Russian Journal of Physical Chemistry B. 12:363-377
ISSN: 1990-7923
1990-7931
DOI: 10.1134/s1990793118030107
Popis: The development of a new direction of research on the production and application of spin-polarized isotopes of noble gases, 3He and 129Xe, is overviewed. Methods of laser hyperpolarization, problems of enhancing the efficiency of laser energy input, and methods of storing hyperpolarized (HP) isotopes are described. Examples and advantages of using HP isotopes in fundamental physics, engineering, medicine, and biology, as well as the progress in the creation of biosensors on hyperpolarized noble gases, are discussed. It has been shown that the study of protein structures and host–guest molecular complexes can prove useful in searching for means of the targeted delivery of radioactive isotopes (radiopharmaceuticals) in nuclear medicine. It is concluded that the progress in modern technologies for producing miniature electronic devices is suggestive of an imminent emergence of small-size scanners for human brain research. At the same time, a high sensitivity of the method is expected to provide the possibility of studying not only the structure of tissues and bloodstream, but also the response of the brain to various stimuli, and even cognitive functions.
Databáze: OpenAIRE
Externí odkaz: