Palladium catalyzed synthesis of sugar-fused indolines via C(sp2)–H/N H activation
| Autor: | Ashish Kumar Verma, Yashwant D. Vankar, Ande Chennaiah, Sateesh Dubbu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Organic Chemistry chemistry.chemical_element Glycoside General Medicine 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry 0104 chemical sciences Analytical Chemistry Catalysis chemistry.chemical_compound chemistry Galactose Sugar Palladium |
| Zdroj: | Carbohydrate Research. 473:57-65 |
| ISSN: | 0008-6215 |
| DOI: | 10.1016/j.carres.2018.12.015 |
| Popis: | A simple Pd(OAc)2 catalyzed strategy for the synthesis of sugar-fused indolines from 2-N-oxalylamido-2-deoxy-C-aryl glycosides is reported by utilizing N-oxalylamido group as an auxiliary via C(sp2)–H/N H Activation. The reaction is successfully applied on glucose as well as galactose derived differently substituted 2-N-oxalylamido-2-deoxy-C-aryl glycosides to give sugar-fused indolines in moderate to good yields. The utility of this strategy in the synthesis of sugar-fused indoles is also described. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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