| Popis: |
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated the background concentration of gadolinium [7440-54-2] in occupationally not exposed persons of the general population without gadolinium application for magnetic resonance imaging (MRI, MRT measurements). Available publications are described in detail. In total, only few publications on the background exposure to gadolinium could be found, some of which used different analytical methods and different sample matrices (urine, blood, serum). Gadolinium concentrations from background exposure were extremely low, often barely measurable and found only just above the respective detection limit. The number of samples in each study is small. All publications reported values below 300 ng/l blood/urine (many significantly below), but there are significant differences in the observed concentrations.According to the limited number of publications determining background levels of gadolinium, the small sample sizes involved and the heterogeneous data situation, no biological reference value (BAR) was derived. |
