An integrated translational analysis summary: Prediction of HERG, isolated wedge preparation, anaesthetized guinea pig and dog towards phase I clinical data for drugs with different QT/TdP risk categories

Autor:	Ard Teisman, Hanne Jansen, David J. Gallacher, Hua Rong Lu, Karel Van Ammel, Henk van der Linde, Jutta Rohrbacher, Vijay Urmaliya
Rok vydání:	2019
Předmět:	Pharmacology Guinea pig Risk category biology Chemistry hERG biology.protein Toxicology Wedge (geometry)
Zdroj:	Journal of Pharmacological and Toxicological Methods. 99:106595
ISSN:	1056-8719
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0caa255b0137556fd8a7af7aa26f2979 https://doi.org/10.1016/j.vascn.2019.05.130 Zobrazit plný text záznamu Full Text from ScienceDirect