A Comparison of Heparin and New Anticoagulants for Cardiopulmonary Bypass Surgery

Autor:	Louis Labrousse, Christian Doutremepuich, Omar Aguejouf, Emmanuelle Belougne-Malfattie
Rok vydání:	1998
Předmět:	Severe bleeding medicine.medical_specialty business.industry medicine.drug_class Anticoagulant Antagonist Hematology General Medicine Heparin Surgery Cardiopulmonary bypass surgery Anesthesia medicine In patient business medicine.drug
Zdroj:	Clinical and Applied Thrombosis/Hemostasis. 4:118-125
ISSN:	1938-2723 1076-0296
Popis:	Heparin is still the major anticoagulant of choice during CPB, but it may cause thrombocytopenia and severe bleeding in patients. In light of these complications, the devel opment of new anticoagulant drugs seemed to be necessary for these patients. Many experimental studies focused on r-hirudin, which presented a less hemorrhagic effect than heparin. How ever, neither antagonist has been shown to reverse this effect.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0ca693bc9a8e1982ff5ae257d0eb0890 https://doi.org/10.1177/107602969800400208 Zobrazit plný text záznamu