Plasma Exchange in Refractory Acute Disseminated Encephalomyelitis Associated with COVID-19: Technical Challenges in a Developing Country
| Autor: | Arpita Khemka, Dipankar Sutar, Durba Biswas, Kalpana Datta, Sumantra Raut, Mousumi Nandi, Mihir Sarkar, A. Banerjee |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty medicine.diagnostic_test Coronavirus disease 2019 (COVID-19) business.industry Encephalomyelitis Developing country Magnetic resonance imaging 030105 genetics & heredity medicine.disease 03 medical and health sciences 0302 clinical medicine Refractory Pediatrics Perinatology and Child Health Acute disseminated encephalomyelitis medicine Coinfection Neurology (clinical) business 030217 neurology & neurosurgery Pediatric population |
| Zdroj: | Journal of Pediatric Neurology. 19:449-451 |
| ISSN: | 1875-9041 1304-2580 |
| DOI: | 10.1055/s-0041-1722927 |
| Popis: | Evaluation of acquired demyelinating syndrome (ADS) without diagnostic biomarkers results in diagnostic and therapeutic challenges in pediatric population. Immune-mediated ADS of childhood responds well to steroid and intravenous immunoglobulin (IVIg) and in refractory cases with plasma exchange. Novel coronavirus disease 2019 (COVID-19) coinfection in such cases imposes technical challenges in management. An 11-year-old girl with quadriparesis and loss of vision and a magnetic resonance imaging (MRI) brain showing acute demyelinating encephalomyelitis (ADEM) and cerebrospinal fluid examination being noncontributory responded well with plasma exchange after failing steroid and IVIg is described. Coinfection with COVID-19 mandating personal protection in a temperate country imposed technical challenges in her management. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|