Radiolysis of selected antibiotics and their toxic effects on various aquatic organisms

Autor:	Myun Joo Lee, Sang Don Kim, Hyun Young Kim, Tae H. Kim, Seung H. Yu
Rok vydání:	2009
Předmět:	Radiation biology medicine.drug_class Chemistry Tetracycline Antibiotics Daphnia magna biochemical phenomena metabolism and nutrition biology.organism_classification Decomposition Vibrio Lincomycin Toxicology Environmental chemistry Radiolysis Toxicity medicine medicine.drug
Zdroj:	Radiation Physics and Chemistry. 78:267-272
ISSN:	0969-806X
DOI:	10.1016/j.radphyschem.2009.01.010
Popis:	This study was conducted to investigate the decomposition of three γ-irradiated antibiotics (e.g., tetracycline, sulfamethazine, and lincomycin) and to compare the toxic effects on Daphnia magna, Vibrio fischeri, and Pseudokirchneriella subcapitata. The median cell growth inhibition concentrations (IC50) of tetracycline, lincomycin, and sulfamethazine for P. subcapitata dramatically increased (e.g., toxicity decreased) after radiolysis. The results demonstrated that γ-radiation treatment was efficient to decompose antibiotics and thereby their toxicity on P. subcaptitata remarkably decreased due to reduced parent compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0c7b79d5324f207286b82f132fff4280 https://doi.org/10.1016/j.radphyschem.2009.01.010 Zobrazit plný text záznamu Full Text from ScienceDirect