Associations of Imaging Markers of Small Vessel Disease and 'Brain Frailty' with Clinical Outcome in Patients with Acute Lacunar Stroke: A Secondary Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial

Autor:	Philip M.W. Bath, John Gommans, Nikola Sprigg, Robert A. Dineen, Enos Trial Investigators, Panos Koumellis, Jennifer L. Becker, Joanna M. Wardlaw, Szabolcs Szatmar, Lesley Cala, Lisa J Woodhouse, Ana M. Casado, Valeria Caso, Hanne Christensen, Alessandro Adami, Eivind Berge, Jason P. Appleton
Rok vydání:	2018
Předmět:	medicine.medical_specialty Prognostic variable Lacunar stroke business.industry Leukoaraiosis Disease medicine.disease Neuroimaging Modified Rankin Scale Internal medicine medicine Dementia cardiovascular diseases business Stroke
Zdroj:	SSRN Electronic Journal.
ISSN:	1556-5068
Popis:	Background: Cerebral small vessel disease (SVD) is a common cause of lacunar stroke, cognitive impairment and dementia. We assessed the association of baseline imaging markers of SVD and 'brain frailty' with functional and cognitive outcomes after acute stroke, including lacunar stroke, in the Efficacy of Nitric Oxide in Stroke (ENOS) trial. Methods: ENOS randomised 4011 patients with acute stroke (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0c70763e3d41fe6b759bafbb797aa149 https://doi.org/10.2139/ssrn.3264985 Zobrazit plný text záznamu