Messung der Hautdicke mittels Hochfrequenzultraschall zur Objektivierung einer Hormonersatztherapie in der Perimenopause
| Autor: | Paul-Gunther Sator, Hönigsmann H, Schmidt Jb, M. O. Sator, Johannes C. Huber |
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| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Ultrasound Urology Hormone replacement therapy (menopause) Low oestradiol Image enhancement Skin thickness Skinfold thickness medicine Radiology Nuclear Medicine and imaging sense organs business Transdermal High frequency ultrasound |
| Zdroj: | Ultraschall in der Medizin. 22:219-224 |
| ISSN: | 1438-8782 0172-4614 |
| Popis: | AIM: The aim of this study was to show the influence of three different hormone replacement therapy regimes (HRT) by comparing the changes in skin thickness. METHOD: Skin thickness was measured using a high-frequency ultrasound system on the inner side of the left upper arm of perimenopausal women with a low oestradiol level (< 45 pg/ml). The patients were allocated to different groups: Group1 (n = 6) received oestradiol merely transdermally; Group 2 (n = 7) was given transdermal oestradiol as well as progesterone vaginally; Group 3 (n = 8) took oral oestradiol and vaginal progesterone; Group 4 (n = 3) served as the control group without therapy. RESULTS: The median value of skin thickness in all HRT-groups increased highly significantly (0.15 mm) after six months (0.91 mm before therapy versus 1.06 mm after six months of HRT), but there was no significant change in the control group. CONCLUSIONS: The study shows that HRT leads to an increase of skin thickness which can be demonstrated by a high-frequency ultrasound. |
| Databáze: | OpenAIRE |
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