Morphological diagnosis of Johne’s disease: a case report in cattle
| Autor: | Chandrakanta Jana, Anil Kumar Sharma, Amol Gurav, Chitra Joshi, Siddharth Gautam |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Pathology General Veterinary 040301 veterinary sciences business.industry Gallbladder Langhans giant cell 04 agricultural and veterinary sciences Small intestine 0403 veterinary science Gross examination 03 medical and health sciences 030104 developmental biology medicine.anatomical_structure Giant cell Medicine Mesenteric lymph nodes Histopathology business Epithelioid cell |
| Zdroj: | TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES. 42:672-675 |
| ISSN: | 1303-6181 1300-0128 |
| Popis: | The present case report deals with the morphological (gross and histopathological) and histochemical characterization of Johne?s disease in a cow. The carcass was presented in a hidebound condition with sunken eyes and with a history of persistent and nonresponsive diarrhea. Necropsy revealed generalized gelatinization of the visceral and peripheral fat. Thorough gross examination unveiled major pathological changes in the digestive tract. The gallbladder was distended, with severely thickened walls and blood mixed with bile. The small intestine was severely congested and the mesenteric lymph nodes were enlarged. The opening of the small intestine showed marked thickening of the intestinal walls, with a corrugated appearance. Diffuse granulomatous lesions were observed in the mesenteric lymph nodes. Histopathological examination revealed severe infiltration of intestinal layers and mesenteric lymph nodes by macrophages, lymphocytes, and epithelioid cells with multiple Langhans giant cells. Ziehl=Neelsen staining demonstrated multiple acid-fast bacilli in the cytoplasm of macrophages from impression smears. |
| Databáze: | OpenAIRE |
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