Numerical investigation of novel microwave applicators based on zero-order mode resonance for hyperthermia treatment of cancer
| Autor: | Jan Vrba, Paul R. Stauffer, David Vrba, Dario B. Rodrigues |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Materials science
Computer Networks and Communications business.industry Aperture Applied Mathematics 0206 medical engineering Resonance Hyperthermia Treatment 020206 networking & telecommunications 02 engineering and technology Radiation 020601 biomedical engineering Resonator Optics Control and Systems Engineering Signal Processing 0202 electrical engineering electronic engineering information engineering Reflection coefficient business Penetration depth Microwave |
| Zdroj: | Journal of the Franklin Institute. 354:8734-8746 |
| ISSN: | 0016-0032 |
| DOI: | 10.1016/j.jfranklin.2016.10.044 |
| Popis: | This paper characterizes three novel microwave applicators based on zero-order mode resonators for use in hyperthermia treatment of cancer. The radiation patterns are studied with numerical simulations in muscle tissue-equivalent model at 434 MHz. The relative performance of the applicators is compared in terms of reflection coefficient, current distribution, power deposition (SAR) pattern, effective field size in 2D and 3D tissue volumes, and penetration depth. One particular configuration generated the most uniform SAR pattern, with 25% SAR covering 84% of the treatment volume extending to 1 cm depth under the aperture, while remaining above 58% coverage as deep as 3 cm under the aperture. Recommendations are made to further optimize this structure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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