The role of CD34-positive cells in the angiogenesis of malignant tissues

Autor: Ivan Reva, Kirill Stegniy, Ekaterina Dvoinikova, Ekaterina Mozhilevskaya, Marina Fleischman, Stanislav Ichenko, Valeriy Tolmachev, Igor Sementsov, Ellada Slabenko, Dmitriy Zvyagintsev, Rodion , Gorbarenko, Aleksandr Zolotov, Tamara Obydennikova, Galina Reva
Rok vydání: 2022
Předmět:
Zdroj: Archiv Euromedica. 12:8-10
ISSN: 2199-885X
Popis: Development of methods for targeted treatment aimed at inhibiting angiogenesis in malignant tissues is of great importance for modern oncology. The features of expression of CD34-positive cells at the border of the tumor and malignant tissue were studied. High expression of CD34-positive cells in small and large vessels during malignancy and is in correlation with the size of the tumor and the age of the disease. A promising target for targeted treatment is VEGF, as the main regulator of angiogenesis during tissue malignancy.
Databáze: OpenAIRE