Assessment of vessels endothelial dysfunction by protease-activated receptors (PARs) signaling in COVID-19 patients

Autor:	Muntadher Ali Jassem, Rana M. Hameed, Hassan Fasil
Rok vydání:	2022
Předmět:	General Nursing Education
Zdroj:	International journal of health sciences. :1064-1070
ISSN:	2550-696X 2550-6978
DOI:	10.53730/ijhs.v6ns9.12413
Popis:	PAR-1-mediated the endothelial disruption that occurs in the context of thromboinflammation. In addition, PAR1 promotes a profibrotic phenotype in fibroblasts, alveolar inflammation, and apoptosis. This is an active area of research; more data are needed to clarify similarities and differences of the PARs and their modulators in Post and Critical cases of COVID-19. Such issues are especially relevant given the potential use PAR-1 as a marker of promote thrombosis and tissue injury through a proposed mechanism between inflammation and thrombosis that was reported previously. This paper would track the theoretical role of PAR-1 as a marker of promote thrombosis in COVID-19 cases by looking for the following questions: What is the Cross Talk Between Thromboinflammation and Protease-activated receptors during Post and Critical cases of COVID-19?
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0c242d30c860b76868d7b89e11831a2f https://doi.org/10.53730/ijhs.v6ns9.12413 Zobrazit plný text záznamu