Nickel Hypersensitivity: A General Review on Clinical Aspects and Potential Co-Morbidities
| Autor: | Foti C, Bonamonte D, Gianfranco Calogiuri, Al-Sowaidi S |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Nickel allergy Allergy business.industry media_common.quotation_subject Dental prosthesis chemistry.chemical_element medicine.disease Cosmetics 030207 dermatology & venereal diseases 03 medical and health sciences Nickel 030104 developmental biology 0302 clinical medicine chemistry Immunology Aseptic bone necrosis medicine business Contact dermatitis Allergic contact dermatitis media_common |
| Zdroj: | Journal of Allergy & Therapy. |
| ISSN: | 2155-6121 |
| DOI: | 10.4172/2155-6121.1000243 |
| Popis: | Allergic contact hypersensitivity to metals is a delayed-type allergy. Although various metals are able to induce an allergic reaction, nickel is the most frequent cause of metal allergy worldwide. The high prevalence of skin sensitization to that metal is the result of an ubiquitous exposure, being contained in different everyday things, such as detergents, cheap jewelry, cosmetics, coins, buttons, zippers, eyeglasses, buckles, clasps, inks, dental prosthesis and foods even. However, nickel is able to induce a wide range of morphological and clinical patterns, ranging from simple allergic contact dermatitis to systemic contact dermatitis and systemic nickel allergy syndrome. The latter seems to be promoted by nickel rich-foods or through endogenous route caused by metal implants which seem to elicit mainly in loco symptoms, sometimes with catastrophic consequences as aseptic bone necrosis following the implantation of hip prosthesis. |
| Databáze: | OpenAIRE |
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