The site of action of the fuzzy locus (fz) in the mouse, as determined by dermal-epidermal recombinations

Autor:	Thomas C. Mayer, James A. Mittelberger, Margaret C. Green
Rok vydání:	1974
Předmět:	integumentary system Molecular Biology Developmental Biology
Zdroj:	Development. 32:707-713
ISSN:	1477-9129 0950-1991
DOI:	10.1242/dev.32.3.707
Popis:	The site of action of the mutation fuzzy (fz) was investigated by the method of dermal- epidermal recombination. Skins from 14-day mutant and normal mouse embryos were sepa- rated into dermal and epidermal components, recombined, and grown in the mouse testis for 14 days. Grafts that contained mutant epidermis as one of the components produced many abnormal hairs characteristic of fuzzy mice. There was no observable effect of the fz locus on the dermis under the conditions of this experiment.
Databáze:	OpenAIRE
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