NHPI-catalyzed electrochemical C–H alkylation of indoles with alcohols to access di(indolyl)methanes via radical coupling

Autor: Bingwen Li, Hongyun Qin, Kelu Yan, Jing Ma, Jianjing Yang, Jiangwei Wen
Rok vydání: 2022
Předmět:
Zdroj: Organic Chemistry Frontiers. 9:6861-6868
ISSN: 2052-4129
DOI: 10.1039/d2qo01498j
Popis: The present indirect electrochemically mediated radical protocol outperforms the traditional Friedel–Crafts route with a broad substrate scope and functional group tolerance, as well as facile gram-scale synthesis without metal contamination.
Databáze: OpenAIRE