Minimum Evaporation Model of Dermatological Delivery Systems. Lamellar Liquid Crystal Formulations Containing Brazilian Nut (Bertholletia excelsaHBK) Vegetable Oil and Guarana Glycolic Extract
| Autor: | Stig E. Friberg, Gislaine Ricci Leonardi, Marlus Chorilli, Michele Fernanda Costa Valarini, Silas Arandas Monteiro e Silva |
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| Rok vydání: | 2014 |
| Předmět: |
Thixotropy
Materials science Chromatography Polymers and Plastics Sorbitan monolaurate food.food Surfaces Coatings and Films chemistry.chemical_compound Vegetable oil food chemistry Pulmonary surfactant Liquid crystal Lyotropic liquid crystal Bertholletia Paullinia cupana Physical and Theoretical Chemistry |
| Zdroj: | Journal of Dispersion Science and Technology. 35:1191-1199 |
| ISSN: | 1532-2351 0193-2691 |
| DOI: | 10.1080/01932691.2013.826586 |
| Popis: | Formulations with lyotropic liquid crystals were prepared from a Brazilian nut vegetable oil, guarana extract and combination of sorbitan monooleate (Span 80) and sorbitan monolaurate ethoxylate EO 20 (Tween 20) in the ratio 1:3 (surfactant component) and their physical–chemical aspects and rheological properties were determined. Compositions with liquid crystals were found in the pseudoternary diagram in a surfactant range of 70–90% and polarized light microscopy, small-angle x-ray scattering (SAXS) showed them to be lamellar. The preparations were furthermore characterized rheologically by shear stress shear rate sweeps finding plastic and pseudoplastic behavior without thixotropy. Electric conductivity and pH measurements demonstrated a potential for future application as dermatological delivery system of the active compounds in the Bertholletia excelsa and Paullinia cupana. |
| Databáze: | OpenAIRE |
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