Bleomycin-lnduced Raynaud's Phenomenon
| Autor: | Linda Bressler, William P. McGuire, Donald Burrows, Lawrence J. Kukla |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Cisplatin
Pathology medicine.medical_specialty Chemotherapy business.industry medicine.medical_treatment Bleomycin Sulfate Dermatology General Medicine Bleomycin medicine.disease Vinblastine chemistry.chemical_compound medicine.anatomical_structure chemistry Cervical lymph nodes Rheumatoid arthritis medicine Vinblastine Sulfate skin and connective tissue diseases business medicine.drug |
| Zdroj: | Archives of Dermatology. 117:604 |
| ISSN: | 0003-987X |
| DOI: | 10.1001/archderm.1981.01650100004005 |
| Popis: | To the Editor.— Teutsch et al 1 reported a case of Raynaud's phenomenon associated with vinblastine sulfate and bleomycin sulfate chemotherapy for testicular carcinoma. Other possible causes of this process were excluded after the following appropriate studies were done: ESR, antinuclear antibody (ANA), rheumatoid arthritis factor, and cryoglobulins. Bleomycin was suggested as the causative agent of this phenomenon, with the subsequent observation that it occurred after single-agent bleomycin therapy. 2 However, in another report the effect was attributed to the toxicity of vinblastine. 3 We have recently treated a patient in whom the events observed seem to implicate bleomycin as the causative agent of Raynaud's phenomenon. Report of a Case.— A 64-year-old man had squamous cell carcinoma of the pharynx and involvement of the cervical lymph nodes bilaterally. The patient was treated with 165 mg of cisplatin (as a 24-hour infusion), 1.6 mg of vincristine sulfate (as an intravenous [IV] |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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